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Ethyl formate

Cas N0. :109-94-4 Molecular formula : C3H6O2
Ethyl formate is an organic compound that is miscible in ethanol, ether, benzene and propylene glycol, slightly soluble in mineral oil and water (decomposes gradually in water), flammable, and its vapor can form explosive mixtures with air. Insoluble in glycerol, easily hydrolyzed into free acid and ethanol in alkaline. It has a spicy pungency and a pineapple-like fruity aroma, as well as a strong rum-like aroma with a slightly bitter taste. In order to allow the use of edible spices, its chemical structure has the properties of active carbonyl and ester groups, and it has reducibility and can carry out ester condensation reaction.
 
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Production use

Ethyl formate is used as a solvent for nitrocellulose, cellulose acetate, etc., as well as fungicides, larvicides and fumigants for food, cigarettes, cereals, dried fruits, etc. As a flavor, ethyl formate can be used to blend the aromas of peach, banana, apple, apricot, pineapple, berries, etc., and can also be used as a spice for butter, brandy, dessert wine, and whisky. Ethyl formate is also an intermediate in organic synthesis. For example, in the pharmaceutical industry, it is used for the production of antitumor drugs Fuxil and vitamin B1; ethyl formate and acetone are condensed in sodium methoxide-xylene solution to obtain sodium acetyl vinyl alcoholate, which is condensed with acetyl glycine ester and then combined with thiocyanate Potassium cyclization can obtain 2-mercaptoimidazole-4-ethyl carboxylate. Ethyl formate is used in the production of drugs such as houttuyniacin, todonin, anadrol, pyrantel, pyridoxine, resorcinol, and fully synthetic anisodamine.

 

 

Storage conditions

 

Store in a cool, dry, well-ventilated warehouse. Keep away from fire and heat sources. The storage temperature should not exceed 30℃. Keep container tightly closed. It should be stored separately from oxidants and alkalis, and should not be mixed. Use explosion-proof lighting and ventilation facilities. Prohibit the use of mechanical equipment and tools that are prone to sparks. Storage areas should be equipped with emergency release equipment and suitable containment materials.

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